Queen Elizabeth National Park covers an area of 764 square miles (1,978 sq km).  The park stretches between Lake Edward in the south up to Lake George in the north with the two lakes being connected by the Kazinga Channel.  The elevation fluctuates from 2,985 to 4,560 feet (910 to 1,390 m) above sea level.

The ecosystems are diverse and feature Acacia savanna, tropical high forests, salt lakes, savanna grasslands, tundra, and wetlands. The lakes are actually partly salt and the two most famous ones are Lake George and Lake Edward.  The landscapes feature the rugged Rwenzori Mountains as the background with remarkable craters nestled into the foothills below the mountains.

Vistas are also provided for panoramic lookouts over the Kazinga Channel and surrounding plains.  The banks of the rivers are frequented by buffalo, elephants, and other ungulates.  Hippos blanket the river waters and crocodiles are frequently basking on the sandy shorelines.  Of course, the densely forested areas make it easy for hiding lion and leopards who wait for victims who come to quench their thirst.

Although the national park is a coveted destination for viewing wildlife, it also offers visitors with aesthetically beautiful landscapes of volcanic cones, craters, and crater lakes.  Some of the more popular wildlife includes lion, buffalo, leopard, elephant, chimpanzee, hippo, and crocodile.  The park is home to over 95 mammalian species and over 600 bird species.